Histopathological findings of renal tissue induced by oxidative stress due to different concentrations of fluoride.

  title={Histopathological findings of renal tissue induced by oxidative stress due to different concentrations of fluoride.},
  author={Q. Luo and H. Cui and H. Deng and P. Kuang and H. Liu and Y. Lu and J. Fang and Z. Zuo and J. Deng and Y. Li and X. Wang and L. Zhao},
  • Q. Luo, H. Cui, +9 authors L. Zhao
  • Published 2017
  • Chemistry, Medicine
  • Oncotarget
  • It has been reported that excessive intake of fluoride can induce renal lesions. However, its pathogenesis is still less understood. Therefore, this study was conducted to investigate oxidative damage and the relationships between the oxidative damage and renal lesions in fluoride-treated mice by using the methods of histopathology, biochemistry, flow cytometry and quantitative real-time polymerase chain reaction (qRT-PCR). A total of 240 ICR mice were randomly divided into four equal groups… CONTINUE READING
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