Histopathological characteristics of spindle-cell proliferative disease in broiler chickens and its experimental reproduction in specific pathogen-free chickens.

@article{Takami2004HistopathologicalCO,
  title={Histopathological characteristics of spindle-cell proliferative disease in broiler chickens and its experimental reproduction in specific pathogen-free chickens.},
  author={Shigeaki Takami and Masanobu Goryo and Toshiaki Masegi and Kosuke Okada},
  journal={The Journal of veterinary medical science},
  year={2004},
  volume={66 3},
  pages={
          231-5
        }
}
The livers and spleens of 45 broiler chickens (33 to 79 days old) suspected of Marek's disease (MD) at meat inspection were collected and examined histopathologically. Macroscopically, they were enlarged from two to three times, and multiple, small, white areas of plaque or infrequent, large, white nodules were observed in most cases. Only 9 birds (20%) were diagnosed with MD based on the histological examination, while the other 35 birds (78%) had tumor-like proliferative lesions in the… CONTINUE READING
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