Histopathologic findings and clinical manifestations in a patient with dysphonia and vocal fold involvement by systemic sclerosis.

Abstract

S ystemic sclerosis (SSc), or systemic scleroderma, is an autoimmune disease characterized by excessive interstitial fibrosis throughout the body. The skin is most frequently affected, resulting in diffuse thickening known as scleroderma (“hard skin”). Common otolaryngologic manifestations include trismus, gastroesophageal reflux disease (GERD), and… (More)
DOI: 10.1001/archoto.2011.119

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