Histopathologic features of genetically determined ovarian cancer.

@article{Shaw2002HistopathologicFO,
  title={Histopathologic features of genetically determined ovarian cancer.},
  author={Patricia A. Shaw and John R McLaughlin and Ronald P. Zweemer and Steven A Narod and Harvey A. Risch and Ren{\'e} H. M. Verheijen and Andy Ryan and Fred H. Menko and Peter Kenemans and Ian J. Jacobs},
  journal={International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists},
  year={2002},
  volume={21 4},
  pages={407-11}
}
Inheritance of germline mutations of BRCA1 or BRCA2 genes account for approximately 10% of ovarian carcinomas, but the characterization of these genetically determined cancers is incomplete. The objective of our study was to characterize the histologic features of ovarian carcinomas associated with germline mutations of BRCA1 and BRCA2. Thirty-two ovarian carcinomas associated with germline BRCA1 or BRCA2 mutations and 40 ovarian carcinomas from patients screened as negative for germline… CONTINUE READING

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