Histopathologic Findings in 5 Patients With Hypomyopathic Dermatomyositis: The Importance of MHC-1 Expression on Myofibers.

@article{ElDokla2015HistopathologicFI,
  title={Histopathologic Findings in 5 Patients With Hypomyopathic Dermatomyositis: The Importance of MHC-1 Expression on Myofibers.},
  author={Ahmed M El-Dokla and Rohit Aggarwal and Chester V. Oddis and Sara T Ali and David Lacomis},
  journal={Journal of clinical neuromuscular disease},
  year={2015},
  volume={17 2},
  pages={52-8}
}
Muscle histopathologic findings in hypomyopathic dermatomyositis (HDM) have not been adequately characterized. We sought to determine the results of conventional and immunohistopathology in HDM. Light microscopic and immunohistochemical analysis was performed on muscle from 5 patients with HDM without muscle weakness. Ages ranged from 49 to 56 years. Creatine kinase level was normal. Electromyography showed mild "myopathic" changes in 2. The median duration of skin disease before biopsy was 18… CONTINUE READING
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