Histones associated with non-nucleosomal rat ribosomal genes are acetylated while those bound to nucleosome-organized gene copies are not.

@article{Mutskov1996HistonesAW,
  title={Histones associated with non-nucleosomal rat ribosomal genes are acetylated while those bound to nucleosome-organized gene copies are not.},
  author={Vesco J Mutskov and Valya R. Russanova and Stefan I Dimitrov and Iliya G. Pashev},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 20},
  pages={11852-7}
}
Acetylation of histones bound to rat rRNA genes has been studied relative to their organization in chromatin, either as canonical nucleosomes, containing the inactive copies, or as anucleosomal nonrepeating structures, corresponding to the transcribed genes (Conconi, A., Widmer, R. M., Koller, T., and Sogo, J. M. (1989) Cell 57, 753-761). Nuclei from butyrate-treated rat tumor cells were irradiated with a UV laser to cross-link proteins to DNA, and the purified covalent complexes were… CONTINUE READING