Histone variants: nuclear function and disease.

Abstract

Histone variants have emerged as important contributors to the regulation of chromatin structure and therefore of almost all DNA-based processes. Hence, these specialized proteins play important roles in transcriptional regulation, cell cycle progression, DNA repair, chromatin stability, chromosome segregation and apoptosis. Due to their evident biological… (More)
DOI: 10.1016/j.gde.2015.12.002

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