Histone variant innovation in a rapidly evolving chordate lineage

@inproceedings{Moosmann2011HistoneVI,
  title={Histone variant innovation in a rapidly evolving chordate lineage},
  author={Alexandra Moosmann and Coen Campsteijn and Pascal Wtc Jansen and Carole M. Nasrallah and Martina Raasholm and Hendrik G. Stunnenberg and Eric M. Thompson},
  booktitle={BMC Evolutionary Biology},
  year={2011}
}
Histone variants alter the composition of nucleosomes and play crucial roles in transcription, chromosome segregation, DNA repair, and sperm compaction. Modification of metazoan histone variant lineages occurs on a background of genome architecture that shows global similarities from sponges to vertebrates, but the urochordate, Oikopleura dioica, a member of the sister group to vertebrates, exhibits profound modification of this ancestral architecture. We show that a histone complement of 47… CONTINUE READING
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