Histone ubiquitination: triggering gene activity.

Abstract

Recently, many of the enzymes responsible for the addition and removal of ubiquitin from the histones H2A and H2B have been identified and characterized. From these studies, it has become clear that H2A and H2B ubiquitination play critical roles in regulating many processes within the nucleus, including transcription initiation and elongation, silencing… (More)
DOI: 10.1016/j.molcel.2008.02.014

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