Histone modifying enzymes: novel disease biomarkers and assay development.

  title={Histone modifying enzymes: novel disease biomarkers and assay development.},
  author={Fei Chun Ma and Chun-Yang Zhang},
  journal={Expert review of molecular diagnostics},
  volume={16 3},
Histones are the chief components of chromatin. When being catalyzed by a series of histone modifying enzymes, histones may undergo various post-translational modifications such as acetylation, methylation, phosphorylation, ubiquitylation and SUMOylation. The dysregulation of histone modifying enzymes will alter the histone post-modification patterns and cause diverse diseases including cancers. Consequently, the histone modifying enzymes have emerged as the promising biomarkers for disease… CONTINUE READING
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Quantum dot-based nanosensors for diagnosis via D ow nl oa de d by [ U ni ve rs ity o f C al if or ni a, S an D ie go

  • BR Knudsen, ML Jepsen, Y-P. Ho
  • enzyme activity measurement. Expert Rev Mol Diagn
  • 2013
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