Histone modifications induced by a family of bacterial toxins.

@article{Hamon2007HistoneMI,
  title={Histone modifications induced by a family of bacterial toxins.},
  author={M{\'e}lanie Anne Hamon and Eric Batsch{\'e} and B{\'e}atrice Regnault and To Nam Tham and Stephanie M. Seveau and Christian Muchardt and Pascale Cossart},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2007},
  volume={104 33},
  pages={13467-72}
}
Upon infection, pathogens reprogram host gene expression. In eukaryotic cells, genetic reprogramming is induced by the concerted activation/repression of transcription factors and various histone modifications that control DNA accessibility in chromatin. We report here that the bacterial pathogen Listeria monocytogenes induces a dramatic dephosphorylation of histone H3 as well as a deacetylation of histone H4 during early phases of infection. This effect is mediated by the major listerial toxin… CONTINUE READING
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References

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Trends Microbiol 14:132–140

  • PM Lieberman
  • 2006

Cell Microbiol 6:1027–1040

  • A Espinosa, JR Alfano
  • 2004

Trends Genet 20:214–220

  • SJ Nowak, VG Corces
  • 2004

Cell Microbiol 4:483–491

  • H Repp, Z Pamukci, +6 authors F Dreyer
  • 2002

Controlling the False Discovery Rate (Blackwell, Oxford)

  • Y Benjamini, Y Hochberg
  • 1995

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