Histone modification and replacement in chromatin activation.

  title={Histone modification and replacement in chromatin activation.},
  author={Mary Grace Goll and Timothy H Bestor},
  journal={Genes & development},
  volume={16 14},
Histones are subject to a complex and dynamic set of covalent modifications that are thought to be involved in the modulation of transcription during development, in X chromosome inactivation in female mammals, and in genome stability and meiotic chromosome dynamics. Histone modifications reported to date include acetylation, phosphorylation, methylation, ADP ribosylation, and ubiquitination (Fig. 1). Multiple residues on each of the four core histones have been identified as potential… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 55 extracted citations

Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology • 2013


Publications referenced by this paper.
Showing 1-10 of 29 references

Similar Papers

Loading similar papers…