Histone methyltransferase 1 regulates the encystation process in the parasite Giardia lamblia.

@article{Salusso2017HistoneM1,
  title={Histone methyltransferase 1 regulates the encystation process in the parasite Giardia lamblia.},
  author={Agostina Salusso and Natacha Zlocowski and Gonzalo F Mayol and Nahuel Zamponi and Andrea Silvana R{\'o}polo},
  journal={The FEBS journal},
  year={2017},
  volume={284 15},
  pages={
          2396-2409
        }
}
In eukaryotes, histone lysine methylation is associated with either active or repressed chromatin states, depending on the status of methylation. Even when the amino-terminus of Giardia lamblia histones diverges from other organisms, these regions contain lysine residues that are potential targets for methylation. When we examined the role of the histone methyltransferase 1 (HMT1) in the regulation of the encystation process by giardial histone methyltransferase 1 (GlHMT1) overexpression or… CONTINUE READING
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