Histone demethylase LSD1 is a folate-binding protein.

@article{Luka2011HistoneDL,
  title={Histone demethylase LSD1 is a folate-binding protein.},
  author={Zigmund Luka and Frank Moss and Lioudmila V. Loukachevitch and Darryl J. Bornhop and Conrad Wagner},
  journal={Biochemistry},
  year={2011},
  volume={50 21},
  pages={4750-6}
}
Methylation of lysine residues in histones has been known to serve a regulatory role in gene expression. Although enzymatic removal of the methyl groups was discovered as early as 1973, the enzymes responsible for their removal were isolated and their mechanism of action was described only recently. The first enzyme to show such activity was LSD1, a flavin… CONTINUE READING