Histone deacetylation-mediated cellular dedifferentiation in Arabidopsis.

@article{Lee2016HistoneDC,
  title={Histone deacetylation-mediated cellular dedifferentiation in Arabidopsis.},
  author={Kyounghee Lee and Ok-Sun Park and Su-jin Jung and Pil Joon Seo},
  journal={Journal of plant physiology},
  year={2016},
  volume={191},
  pages={
          95-100
        }
}
Chromatin structure determines the accessibility of transcriptional regulators to target DNA and contributes to regulation of gene expression. Posttranslational modifications of core histone proteins underlie the reversible changes in chromatin structure. Epigenetic regulation is closely associated with cellular differentiation. Consistently, we found that histone deacetylation is required for callus formation from leaf explants in Arabidopsis . Treatment with trichostatin A (TSA) led to… CONTINUE READING

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