Histone deacetylation directs DNA methylation in survivin gene silencing.

@article{Ma2011HistoneDD,
  title={Histone deacetylation directs DNA methylation in survivin gene silencing.},
  author={Ai-niu Ma and Jie Lu and Xiang-jun Zhou and Yongxiang Wang},
  journal={Biochemical and biophysical research communications},
  year={2011},
  volume={404 1},
  pages={
          268-72
        }
}
  • A. Ma, Jie Lu, Yongxiang Wang
  • Published 7 January 2011
  • Biology, Chemistry
  • Biochemical and biophysical research communications
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17 Citations
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17 Citations

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Citation Type

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TLDR
It is provided evidences that a critical role for cPouV activation/repression by DNA methylation and/or histone modifications is involved in the pluripotency maintenance and differentiation process of chick EG.
DNA Methylation and Histone Modifications Are the Molecular Lock in Lentivirally Transduced Hematopoietic Progenitor Cells
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It is demonstrated that LV carrying green fluorescent protein (GFP) reporter gene driven by cytomegalovirus (CMV) promoter was subjected to transgene silencing after transduction into HPCs.
Effect of trichostatin A on CNE2 nasopharyngeal carcinoma cells--genome-wide DNA methylation alteration.
TLDR
It is concluded that TSA inhibits CNE2 cell growth and induces apoptosis in vitro involving genome-wide DNA methylation alteration, so that it has promising application prospects in treatment of NPC in vivo.
Trichostatin A and sirtinol suppressed survivin expression through AMPK and p38MAPK in HT29 colon cancer cells.
Epigenetic mechanism of survivin dysregulation in human cancer
TLDR
The current article provides a literature review on the impact of DNA methylation and histone modifications, including specific lysine methylation, demethylation, and acetylation on the expression of Survivin.
DNA methyl transferase I acts as a negative regulator of allergic skin inflammation.
Cross-Species Analysis of Genic GC3 Content and DNA Methylation Patterns
TLDR
It is proposed that the opposite effects of methylation and compositional gradients along coding regions of GC3-poor andGC3-rich genes are the products of several competing processes.
Epigenetics Interplay between DNA Methylation and Histone Modifications in Breast Cancer
TLDR
Epigenetics Interplay between DNA Methylation and Histone Modifications in Breast Cancer is a heterogeneous disease that results from the genetic and epigenetic events, including activation of oncogenes and inactivation of tumor suppressing genes.
Characteristic and evolution of HAT and HDAC genes in Gramineae genomes and their expression analysis under diverse stress in Oryza sativa.
TLDR
Gene structure, protein property and protein motif composition illustrated the conservation and variation of HATs and HDACs in Gramineae and provided the basis for further identification of candidate OsHAT and OsHDAC genes that may be utilized in regulating growth and development and improving crop tolerance to abiotic stress.
BIRC5 promoter SNPs do not affect nuclear survivin expression and survival of malignant pleural mesothelioma patients
TLDR
It is observed that BIRC5 −241C > T polymorphism had a significant effect on patient age at diagnosis, but no significant effects of nuclear survivin expression or genotype/haplotype on overall survival were observed.
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