Histone deacetylases 1, 6 and 8 are critical for invasion in breast cancer.

Abstract

Histone deacetylases (HDACs) are associated with the development and progression of cancer, but it is not known which of the HDAC isoforms play important roles in breast cancer metastasis. This study identified the specific HDAC isoforms that are necessary for invasion and/or migration in human breast cancer cell lines. MDA-MB-231 cells were significantly… (More)
DOI: 10.3892/or.2011.1236

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