Histone deacetylase inhibition improves differentiation of dendritic cells from leukemic blasts of patients with TEL/AML1-positive acute lymphoblastic leukemia.

Abstract

Histone deacetylase inhibitors (HdI) could potentially improve the differentiation of leukemic dendritic cells (DC). Therefore, bone marrow samples from 100 children with acute lymphoblastic leukemia (ALL) were cultured in the cytokines TNF-alpha, GM-CSF, c-kit ligand, and fetal liver tyrosine kinase 3 ligand, with or without IL-3 and -4 and after… (More)
DOI: 10.1189/jlb.0808469

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@article{Schmidt2009HistoneDI, title={Histone deacetylase inhibition improves differentiation of dendritic cells from leukemic blasts of patients with TEL/AML1-positive acute lymphoblastic leukemia.}, author={Kerstin Schmidt and K. H. Seeger and Carmen Scheibenbogen and Roderich Bender and Majd Abdulla and Sina S{\"{u}ssmilch and Abdulagabar Salama and Anja I. S. Moldenhauer}, journal={Journal of leukocyte biology}, year={2009}, volume={85 3}, pages={563-73} }