Histone deacetylase 2 is involved in µ‑opioid receptor suppression in the spinal dorsal horn in a rat model of chronic pancreatitis pain.

Abstract

Chronic pain occurs in ~85-90% of chronic pancreatitis (CP) patients. However, as the pathogenesis of CP pain remains to be fully understood, the current therapies for CP pain remain inadequate. Emerging evidence has suggested that the epigenetic modulations of genes are involved in chronic pain. In the present study, intrapancreatic trinitrobenzene… (More)
DOI: 10.3892/mmr.2017.8245

Cite this paper

@article{Liao2018HistoneD2, title={Histone deacetylase 2 is involved in µ‑opioid receptor suppression in the spinal dorsal horn in a rat model of chronic pancreatitis pain.}, author={Yong-Hui Liao and Jian Wang and Yan-yan Wei and Ting Zhang and Yong Zhang and Zhong-Fu Zuo and Xiao-yu Teng and Yun-qing Li}, journal={Molecular medicine reports}, year={2018}, volume={17 2}, pages={2803-2810} }