Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy

@inproceedings{Haery2015HistoneAA,
  title={Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy},
  author={Leila Haery and Ryan C. Thompson and Thomas D Gilmore},
  booktitle={Genes & cancer},
  year={2015}
}
The development of B and T cells from hematopoietic precursors and the regulation of the functions of these immune cells are complex processes that involve highly regulated signaling pathways and transcriptional control. The signaling pathways and gene expression patterns that give rise to these developmental processes are coordinated, in part, by two opposing classes of broad-based enzymatic regulators: histone acetyltransferases (HATs) and histone deacetylases (HDACs). HATs and HDACs can… CONTINUE READING

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