Histone acetyltransferase p300 regulates the expression of human pituitary tumor transforming gene (hPTTG).

@article{Li2009HistoneAP,
  title={Histone acetyltransferase p300 regulates the expression of human pituitary tumor transforming gene (hPTTG).},
  author={Tian Li and Hui Huang and Binlu Huang and Baiqu Huang and Jun Lu},
  journal={Journal of genetics and genomics = Yi chuan xue bao},
  year={2009},
  volume={36 6},
  pages={335-42}
}
The human pituitary tumor transforming gene (hPTTG) serves as a marker for malignancy grading in several cancers. hPTTG is involved in multiple cellular pathways including cell transformation, apoptosis, DNA repair, genomic instability, mitotic control and angiogenesis induction. However, the molecular mechanisms underlying hPTTG regulation have not been fully explored. In this study, we found that overexpression of histone acetyltransferase (HAT) p300 upregulated hPTTG at the levels of… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 28 references

Isolation and characterization of a pituitary tumor-transforming gene (PTTG).

Molecular endocrinology • 1997
View 5 Excerpts
Highly Influenced

Compilation of vertebrate-encoded transcription factors

Nucleic Acids Research • 1992
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…