Histone H3 globular domain acetylation identifies a new class of enhancers

@inproceedings{Pradeepa2016HistoneHG,
  title={Histone H3 globular domain acetylation identifies a new class of enhancers},
  author={Madapura M Pradeepa and G. R. Grimes and Yatendra Kumar and Gabrielle Olley and Gillian C.A. Taylor and Robert H. Schneider and Wendy A. Bickmore},
  booktitle={Nature Genetics},
  year={2016}
}
Histone acetylation is generally associated with active chromatin, but most studies have focused on the acetylation of histone tails. Various histone H3 and H4 tail acetylations mark the promoters of active genes. These modifications include acetylation of histone H3 at lysine 27 (H3K27ac), which blocks Polycomb-mediated trimethylation of H3K27 (H3K27me3… CONTINUE READING

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