Histone H3 K36 methylation is associated with transcription elongation in Schizosaccharomyces pombe.

@article{Morris2005HistoneHK,
  title={Histone H3 K36 methylation is associated with transcription elongation in Schizosaccharomyces pombe.},
  author={Stephanie A V Morris and Yoichiro Shibata and Ken-ichi Noma and Yuko Tsukamoto and E. Dixon Warren and Brenda Temple and Shiv I S Grewal and Brian D. Strahl},
  journal={Eukaryotic cell},
  year={2005},
  volume={4 8},
  pages={
          1446-54
        }
}
Set2 methylation of histone H3 at lysine 36 (K36) has recently been shown to be associated with RNA polymerase II (Pol II) elongation in Saccharomyces cerevisiae. However, whether this modification is conserved and associated with transcription elongation in other organisms is not known. Here we report the identification and characterization of the Set2 ortholog responsible for K36 methylation in the fission yeast Schizosaccharomyces pombe. We find that similar to the budding yeast enzyme, S… CONTINUE READING
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