Histone H1 Is required for proper regulation of pyruvate decarboxylase gene expression in Neurospora crassa.

@article{Folco2003HistoneHI,
  title={Histone H1 Is required for proper regulation of pyruvate decarboxylase gene expression in Neurospora crassa.},
  author={Hern{\'a}n Diego Folco and Michael Freitag and Ana Ram{\'o}n and Esteban D. Temporini and Mar{\'i}a Elena Alvarez and Irene Garc{\'i}a and Claudio Scazzocchio and Eric U Selker and Alberto Rosa},
  journal={Eukaryotic cell},
  year={2003},
  volume={2 2},
  pages={341-50}
}
We show that Neurospora crassa has a single histone H1 gene, hH1, which encodes a typical linker histone with highly basic N- and C-terminal tails and a central globular domain. A green fluorescent protein-tagged histone H1 chimeric protein was localized exclusively to nuclei. Mutation of hH1 by repeat-induced point mutation (RIP) did not result in detectable defects in morphology, DNA methylation, mutagen sensitivity, DNA repair, fertility, RIP, chromosome pairing, or chromosome segregation… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

Similar Papers

Loading similar papers…