Histone Crosstalk Directed by H 2 B Ubiquitination Is Required for Chromatin Boundary Integrity Meiji

Abstract

Genomic maps of chromatin modifications have provided evidence for the partitioning of genomes into domains of distinct chromatin states, which assist coordinated gene regulation. The maintenance of chromatin domain integrity can require the setting of boundaries. The HS4 insulator element marks the 39 boundary of a heterochromatin region located upstream… (More)

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