• Corpus ID: 14777483

Histomorphometry of the human optic nerve.

  title={Histomorphometry of the human optic nerve.},
  author={Jost Bruno Jonas and J A M{\"u}ller-Bergh and Ursula Schl{\"o}tzer-Schrehardt and Gottfried O. H. Naumann},
  journal={Investigative ophthalmology \& visual science},
  volume={31 4},
This study was undertaken to measure number, diameter and distribution of nerve fibers in normal human optic nerves. [] Key Method Twenty-two optic nerves of 19 subjects aged between 20 and 75 years were histomorphometrically examined using semithin sections obtained in a distance of 2 to 5 mm behind the globe. The mean nerve fiber count was 1,159,000 +/- 196,000 with a minimum of 816,000 and a maximum of 1,502,000. The significant (P = 0.025) loss per year of age was approximately 5426 nerve fibers. For…

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