Histomorphometric and microCT analysis of bone biopsies from postmenopausal osteoporotic women treated with strontium ranelate.

@article{Arlot2008HistomorphometricAM,
  title={Histomorphometric and microCT analysis of bone biopsies from postmenopausal osteoporotic women treated with strontium ranelate.},
  author={Monique E. Arlot and Yebin Jiang and Harry K. Genant and Jenny Zhao and Brigitte Burt-Pichat and J. P. Roux and Pierre Dominique Delmas and Pierre Jean Meunier},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2008},
  volume={23 2},
  pages={215-22}
}
UNLABELLED Strontium ranelate is a new anti-osteoporotic treatment. On bone biopsies collected from humans receiving long-term treatment over 5 yr, it has been shown that strontium ranelate has good bone safety and better results than placebo on 3D microarchitecture. Hence, these effects may explain the decreased fracture rate. INTRODUCTION Strontium ranelate's mode of action involving dissociation of bone formation and resorption was shown in preclinical studies and could explain its… CONTINUE READING
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