Histometric study of socket healing after tooth extraction in rats treated with diclofenac.

@article{Yugoshi2002HistometricSO,
  title={Histometric study of socket healing after tooth extraction in rats treated with diclofenac.},
  author={Luciana Ibara Yugoshi and Miguel Angel Sala and Luiz Guilherme Brentegani and Teresa L{\'u}cia Lamano Carvalho},
  journal={Brazilian dental journal},
  year={2002},
  volume={13 2},
  pages={92-6}
}
The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective… CONTINUE READING

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