Histology without formalin?

@article{Buesa2008HistologyWF,
  title={Histology without formalin?},
  author={Ren{\'e} J Buesa},
  journal={Annals of diagnostic pathology},
  year={2008},
  volume={12 6},
  pages={387-96}
}
Because formalin is toxic, carcinogenic, and a poor preserver of nucleic acids, for more than 20 years, there have been numerous attempts to find a substitute, with as many different alternative fixatives, none totally successful. With a fast penetration, formaldehyde is a slow and reversible fixative that requires 24 to 48 hours to completely bind to tissue; thus, any surgical specimen arriving to the laboratory between 8 AM and 4 PM and processed conventionally for the slides to be ready the… CONTINUE READING

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