Corpus ID: 3564850

Histology and Histopathology Apoptosis and autophagy in nigral neurons of patients with Parkinson ' s disease

@inproceedings{Anglade2010HistologyAH,
  title={Histology and Histopathology Apoptosis and autophagy in nigral neurons of patients with Parkinson ' s disease},
  author={P. Anglade and S. Vyas and Javoy-Agid and M. Herrero and P. Michel and J. Marquez and A. Mouatt-Prigent and M. Ruberg and Hirsch and Y. Agid},
  year={2010}
}
Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive cell loss confined mostly to dopaminergic neurons of the substantia nigra. Several factors, including oxidative stress, and decreased activity of complex 1 mitochondrial respiratory chain, are involved in the degenerative process. Yet, the underlying mechanisms leading to dopaminergic cell loss remain elusive. Morphological assessrnent for different modes of cell death: apoptosis, necrosis or autophagic… Expand

Figures and Tables from this paper

References

SHOWING 1-10 OF 31 REFERENCES
Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models
  • 623
  • PDF
Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ
  • 204
Parkinson's disease: A disorder due to nigral glutathione deficiency?
  • 722
Apoptosis in substantia nigra following developmental striatal excitotoxic injury.
  • 130
  • PDF
...
1
2
3
4
...