Histological grading of colorectal cancer: a simple and objective method.

  title={Histological grading of colorectal cancer: a simple and objective method.},
  author={Hideki Ueno and Hidetaka Mochizuki and Yojiro Hashiguchi and Megumi Ishiguro and Yoshiki Kajiwara and Taichi Sato and Hideyuki Shimazaki and Kazuo Hase and Ian C. Talbot},
  journal={Annals of surgery},
  volume={247 5},
OBJECTIVE Tumor grade employed for colorectal cancer has long been based on the degree of differentiation, which is difficult to judge objectively. The aim of this study was to determine whether the extent of the poorly differentiated component (POR) could be a valuable criterion for a grading system. PATIENTS AND METHODS A total of 1075 patients with advanced colorectal cancer were pathologically reviewed. POR was newly defined as a region in which a cancer has no glandular formation… CONTINUE READING
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