Histological evaluation of the adrenal glands of seven dogs with hyperadrenocorticism treated with trilostane.

@article{Reusch2007HistologicalEO,
  title={Histological evaluation of the adrenal glands of seven dogs with hyperadrenocorticism treated with trilostane.},
  author={Claudia E. Reusch and N. S. Sieber‐Ruckstuhl and Monique Wenger and Hartmut Lutz and Aurel Perren and Andreas Pospischil},
  journal={The Veterinary record},
  year={2007},
  volume={160 7},
  pages={
          219-24
        }
}
The lesions in the adrenal glands of seven dogs with hyperadrenocorticism that had been treated with trilostane were studied histologically. The glands of the six dogs with pituitary-dependent hyperadrenocorticism had moderate to severe cortical hyperplasia that was either diffuse or nodular. The lesions were more pronounced in the zona fasciculata than in the zona reticularis, and the zona glomerulosa was normal. In the dog with a functional adrenal tumour the non-tumour bearing adrenal gland… CONTINUE READING

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  • Medicine
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  • 2010
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A comparison of once and twice daily administration of trilostane to dogs with hyperadrenocorticism.

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