Histological categorisation of fibrotic cancer stroma in advanced rectal cancer.

  title={Histological categorisation of fibrotic cancer stroma in advanced rectal cancer.},
  author={Hideki Ueno and Amanda M. Jones and Kay H Wilkinson and Jeremy R. Jass and Ian C. Talbot},
  volume={53 4},
BACKGROUND AND AIMS Based on conflicting reports regarding the role of the fibrotic stromal response in cancer development--namely, that a desmoplastic reaction can favour either the host or the tumour--it is clear that the role of the stromal response is varied. We have classified the fibrotic stroma of rectal adenocarcinoma penetrating the muscularis propria, based on histologically identified stromal components. METHODS Three categories of stroma were used: mature-when the stroma was… CONTINUE READING


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Histological indices in biopsy specimens for estimating the probability of extended local spread in rectal cancer

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