Corpus ID: 35323577

Histological and histochemical examinations of myocardium of rats kept on low-magnesium diet and receiving methotrexate.

@article{Wutzen1990HistologicalAH,
  title={Histological and histochemical examinations of myocardium of rats kept on low-magnesium diet and receiving methotrexate.},
  author={J. Wutzen},
  journal={Materia medica Polona. Polish journal of medicine and pharmacy},
  year={1990},
  volume={22 3},
  pages={
          156-61
        }
}
  • J. Wutzen
  • Published 1990
  • Medicine
  • Materia medica Polona. Polish journal of medicine and pharmacy
  • Methotrexate administration in 1 mg/kg doses intraperitoneally twice weekly for six weeks caused in rat myocardium the following focal, not very intense, histological and histochemical changes from the third week of the experiment on: focal increasing eosinophilia and fuchsinophilia of myocyte cytoplasm, undulating shape of myocardial fibres, contraction nodes, in the sixth week small necrotic foci with associated infiltrations composed of mononuclear cells, presence of p.a.S. positive… CONTINUE READING