Histologic grading of breast carcinoma. A reproducibility study.

@article{Dalton1994HistologicGO,
  title={Histologic grading of breast carcinoma. A reproducibility study.},
  author={Leslie W. Dalton and David L. Page and William D. Dupont},
  journal={Cancer},
  year={1994},
  volume={73 11},
  pages={
          2765-70
        }
}
BACKGROUND A concern with the histologic grading of breast cancer is that tumor grading is a subjective evaluation that may have problems with reproducibility. METHODS A single slide from 10 invasive breast cancers was submitted to 25 pathologists who practice in six separate groups. Pathologists graded the tumors using a modified Bloom-Richardson (B-R) scheme, and the results were compared. RESULTS In 8 of the 10 cases, there was greater than 87% agreement by the pathologists as to the… CONTINUE READING

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