Histologic grading is an independent prognostic factor in invasive lobular carcinoma of the breast

@article{Rakha2007HistologicGI,
  title={Histologic grading is an independent prognostic factor in invasive lobular carcinoma of the breast},
  author={Emad A Rakha and Maysa E. El-Sayed and Sindhu Menon and Andrew R. Green and Andrew H. S. Lee and Ian O. Ellis},
  journal={Breast Cancer Research and Treatment},
  year={2007},
  volume={111},
  pages={121-127}
}
Invasive lobular carcinoma (ILC) comprises approximately 5–15% of breast cancers and appears to have a distinct biology. As it is less common than invasive ductal carcinoma, few studies of large size have addressed the value of assessment of histologic grade in ILC. Methods: This study is based on a large and well-characterised consecutive series of breast cancer (4,987 cases), from a single institution, with a long-term follow-up to assess the prognostic value of routine assessment of… CONTINUE READING

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a review of the literature

Valero V Gonzalez-Angulo AM et al Prognosis Hanrahan EO, 1 managementofpatientswithnode-negativeinvasivebreas, bN0M0 T1a
J Clin Oncol 24:2113–2122 126 Breast Cancer Res Treat • 2008
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