Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome.

@article{Caldwell2014HistologicEG,
  title={Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome.},
  author={Julie M Caldwell and Margaret H. Collins and Emily M. Stucke and Philip E. Putnam and James P Franciosi and Jonathan P. Kushner and Juan Pablo Abonia and Marc E Rothenberg},
  journal={The Journal of allergy and clinical immunology},
  year={2014},
  volume={134 5},
  pages={1114-24}
}
BACKGROUND The definition of eosinophilic gastritis (EG) is currently limited to histologic EG based on the tissue eosinophil count. OBJECTIVE We aimed to provide additional fundamental information about the molecular, histopathologic, and clinical characteristics of EG. METHODS Genome-wide transcript profiles and histologic features of gastric biopsy specimens, as well as blood eosinophil counts, were analyzed in patients with EG and control subjects (n = 15 each). RESULTS The peak… CONTINUE READING