Histologic and biochemical changes during the evolution of chronic rejection of liver allografts.

@article{Neil2002HistologicAB,
  title={Histologic and biochemical changes during the evolution of chronic rejection of liver allografts.},
  author={Desley A H Neil and Stefan G. Hubscher},
  journal={Hepatology},
  year={2002},
  volume={35 3},
  pages={639-51}
}
Criteria for histologic diagnosis of chronic rejection (CR) are based on changes seen late in the disease process that are likely to be irreversible and unresponsive to treatment. Changes occurring during the evolution of CR are less clearly defined. The serial biopsy specimens, failed allografts, and biochemical profiles of 28 patients who underwent retransplantation for CR were examined with the aim of identifying histologic and biochemical features that were present during the early stages… CONTINUE READING
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