Histologic and Immunohistochemical Studies of Granular Cell Tumors in Seven Dogs, Three Cats, One Horse, and One Bird

@article{Patnaik1993HistologicAI,
  title={Histologic and Immunohistochemical Studies of Granular Cell Tumors in Seven Dogs, Three Cats, One Horse, and One Bird},
  author={A. Patnaik},
  journal={Veterinary Pathology},
  year={1993},
  volume={30},
  pages={176 - 185}
}
  • A. Patnaik
  • Published 1993
  • Biology, Medicine
  • Veterinary Pathology
In a retrospective study, granular cell tumors in six dogs (Nos. 1–6), three cats (Nos. 1–3), one horse (No. 1), and one cockatiel (Nymphicus hollandicus) (No. 1) and a meningioma with a granular cell component in one dog (No. 7) were examined histologically and immunohistochemically. These tumors were identified by histologic examination of surgical biopsy specimens, except in the horse, in which the tumor was an incidental finding at necropsy. These diagnoses were initially made by more than… Expand
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References

SHOWING 1-10 OF 79 REFERENCES
Granular cell tumors of the vulva.
TLDR
No dependable microscopic features could be identified to distinguish benign GCT from its more aggressive variant, however, Feulgen DNA histomorphometry demonstrated aneuploidy in the patient with apparent lung metastases, whereas the tumors from patients with a benign course as well as from the customer with multiorgan involvement were diploid. Expand
Oral granular cell tumors: a clinicopathologic and immunocytochemical study.
TLDR
It is concluded that the oral NGGCT is a tumor positive for S-100 protein that may arise from muscle or nerve sheath and is not homogenous for immunocytochemical markers. Expand
Rhabdoid Tumor of Kidney: A Report of 111 Cases from the National Wilms' Tumor Study Pathology Center
TLDR
There was no evidence of a histogenetic relationship to Wilms' tumor, although RTK may overlap with mesoblastic nephroma and clear cell sarcoma, and several findings suggested that RTK might arise from primitive cells involved in formation of the renal medulla. Expand
Immunoreactivity of granular cell lesions of skin, mucosa, and jaw
TLDR
The extent of immunologic heterogeneity of granular cell lesions from a wide variety of sites in skin, mucosa, and jaw is determined and HLA‐DR by granular cells is believed to be unrelated to cellular origin but rather to some common immunologic function. Expand
Granular cell tumour (myoblastoma) in the lung of a horse.
TLDR
It appears that the site of occurrence of granular cell tumours varies between species, with the lung of the horse and the tongue of the dog being major sites. Expand
Immunohistochemical profile of meningiomas and their histological subtypes.
TLDR
Seventy-seven cases of meningioma, selected on the basis of their histologic subtypes, and nine cases of neurilemoma were analyzed immunohistochemically for the presence of the five classes of intermediate filament proteins, neuron-specific enolase, protein S-100, epithelial membrane antigen (EMA), and HNK-1. Expand
Granular cell tumor. Immunohistochemical analysis of 21 benign tumors and one malignant tumor.
TLDR
Findings support a Schwann cell origin for nongingival GCTs and illustrate a useful panel of commercially available antibodies to diagnose these distinctive tumors. Expand
Intrathoracic granular cell tumour in a dog.
  • G. Foley
  • Medicine
  • Journal of comparative pathology
  • 1988
TLDR
The predilection site in theDog is the tongue and this is the first report of an intrathoracic, pleural site of granular cell tumours in the dog. Expand
Atypical Location of Granular Cell Tumors in Two Dogs
1 Altman NH, Lamborn PB: Lymphocytic leukemia in a ferret (Mustelafuro). Vet Pathol21:361-362, 1984 2 Brodey RS, Riser WH, van der Heul RO: Canine skeletal chondrosarcoma: a clinicopathologic studyExpand
Granular Basal Cell Tumors in the Skin of Three Dogs: A Distinct Histopathologic Entity
  • R. Seiler
  • Biology, Medicine
  • Veterinary pathology
  • 1982
TLDR
Granular cell variants of cutaneous basal cell tumors from three dogs are described, characterized by classical basal cells as well as granular cells with numerous cytoplasmic granules that resemble the granules of granular cell “myoblastoma” although granular basal cells are of epithelial origin. Expand
...
1
2
3
4
5
...