Histologic Investigation of the Macula Flava of the Human Newborn Vocal Fold

@article{Sato1995HistologicIO,
  title={Histologic Investigation of the Macula Flava of the Human Newborn Vocal Fold},
  author={K. Sato and Masanori Hirano},
  journal={Annals of Otology, Rhinology \& Laryngology},
  year={1995},
  volume={104},
  pages={556 - 562}
}
  • K. Sato, M. Hirano
  • Published 1 July 1995
  • Medicine
  • Annals of Otology, Rhinology & Laryngology
This investigation was carried out to determine the histologic structure of the maculae flavae of human newborn vocal folds. Light microscopic and transmission electron microscopic observations were made with excised human newborn larynges. The results are summarized as follows. 1) Immature maculae flavae were present at the anterior and posterior ends of the bilateral vocal folds. 2) They were round in shape and about 1 × 1 × 1 mm in size. 3) The maculae flavae were composed of fibroblasts… 
Age-Related Changes of the Macula Flava of the Human Vocal Fold
  • K. Sato, M. Hirano
  • Biology, Medicine
    The Annals of otology, rhinology, and laryngology
  • 1995
TLDR
A decrease in the number and activation of fibroblasts in maculae flavae indicates decreased synthesis of fibrous components in the vocal fold mucosa, which influences the viscoelasticity and stiffness of vibrating tissue and contributes partially to aging of the voice.
Comparative Histology of the Maculae Flavae of the Vocal Folds
TLDR
The HMF contributes to the formation of the vocal ligaments and the layered structure of human vocal folds and the density of both in HMF was much greater than that in CMF.
Fine Structure of the Human Newborn and Infant Vocal Fold Mucosae
TLDR
During infancy, the extracellular matrices synthesized in the maculae flavae appear in the membranous portion of the vocal fold, each at a different time, so as to initiate the 3-dimensional formation ofThe vocal fold mucosa.
Histologic Structure and Development of the Laryngeal Macula Flava
The laryngeal maculae flavae (MF) have been previously described as cellular condensations at the extremities of the vocal cords, but the exact nature and role of the MF are unknown. The purpose of
[Ultrastructure of the mucous membrane of the human newborn vocal folds].
TLDR
The newborn vocal fold mucosa lacked not only a vocal ligament but also adequate viscoelasticity for vibration and ground substance was abundant in the lamina propria.
Electron Microscopic Investigation of Sulcus Vocalis
  • K. Sato, M. Hirano
  • Biology, Medicine
    The Annals of otology, rhinology, and laryngology
  • 1998
TLDR
The quality and quantity of the fibrous components were changed in the mucosa of sulcus vocalis, owing in part to dysfunction of the Fibroblasts and abnormal fibrogenesis in the maculae flavae.
Macula Flava and Vocal Fold Stellate Cells of the Human Adult Vocal Fold
1. Human adult maculae flavae are dense masses of cells and extracellular matrices located at the anterior and posterior ends of the membranous portion of the bilateral vocal folds. 2.
Macula Flava of the Human Newborn Vocal Fold
TLDR
The results of these studies are consistent with the hypothesis that the cells including the vocal fold stellate cells in the human newborn maculae flavae are tissue stem cells or progenitor cells of theHuman newborn vocal fold mucosa as a vibrating tissue.
Functional Histology of the Macula Flava in the Human Vocal Fold – Part 2: Its Role in the Growth and Development of the Vocal Fold
TLDR
Human MFe including VFSCs were inferred to be involved in the metabolism of EM, essential for the viscoelasticity of the human VFM, and are considered to be an important structure in the growth and development of thehuman VFM.
Fibroblasts in the human vocal fold mucosa: an ultrastructural study of different age groups.
TLDR
Histological changes of fibroblasts in the VF mucosa are one of the important causes of the change in voice quality with ageing, and geriatric changes in the vocal ligament can be attributed to the activities and the presence of ageing processes in fibro Blasts of geriatric Vf mucosa.
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Histologic Investigation of the Macula Flava of the Human Vocal Fold
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  • Medicine
    The Annals of otology, rhinology, and laryngology
  • 1995
TLDR
An investigation was carried out to determine the histologic structure of the maculae flavae of human adult vocal folds, which seem to control the synthesis of fibrous components in the vocal ligament.
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