Histologic Findings of Severe/Therapy-Resistant Asthma From Video-assisted Thoracoscopic Surgery Biopsies.

@article{Bittar2017HistologicFO,
  title={Histologic Findings of Severe/Therapy-Resistant Asthma From Video-assisted Thoracoscopic Surgery Biopsies.},
  author={Humberto E Trejo Bittar and Daniel Doberer and Mitra Mehrad and Diane C. Strollo and Joseph K. Leader and Sally Wenzel and Samuel A. Yousem},
  journal={The American journal of surgical pathology},
  year={2017},
  volume={41 2},
  pages={
          182-188
        }
}
The histologic changes occurring in severe/therapy-resistant asthma (SA) as defined by the European Respiratory Society/American Thoracic Society guidelines, particularly at the level of the distal airways are unknown. This study describes the clinical, radiologic, and histologic characteristics of 29 SA patients who underwent video-assisted thoracoscopic surgery lung biopsy. Pathologic observations were correlated with clinical features, especially the presence of autoimmune disease (AID) (15… CONTINUE READING
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