Histocultures of Patient Head and Neck Tumors for Pharmacodynamics Studies

Abstract

This investigation was to establish a clinically relevant experimental model to evaluate the pharmacodynamics of drugs used for head and neck cancers. A total of 83 surgical samples of primary and lymph nodal metastatic tumors was obtained from 66 patients. Fragments of these tumors were cultured on a collagen gel matrix. The tumor cell labeling index (LI… (More)
DOI: 10.1023/A:1018935628085

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