Histochemical study of intestinal mucins after administration of silver nanoparticles in Sprague–Dawley rats

@article{Jeong2009HistochemicalSO,
  title={Histochemical study of intestinal mucins after administration of silver nanoparticles in Sprague–Dawley rats},
  author={Gil Nam Jeong and Un Bock Jo and Hyeon Yeol Ryu and Yong Soon Kim and Kyung Seuk Song and Il Je Yu},
  journal={Archives of Toxicology},
  year={2009},
  volume={84},
  pages={63-69}
}
To investigate the effects of silver nanoparticles on the histological structure and properties of the mucosubstances in the intestinal mucosa, Sprague–Dawley rats were divided into four groups (10 rats in each group): vehicle control, low-dose group (30 mg/kg), middle-dose group (300 mg/kg), and high-dose group (1,000 mg/kg), and administered silver nanoparticles (60 nm) for 28 days, following OECD test guideline 407 and using GLP. The control sections contained no silver nanoparticles… CONTINUE READING

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