Histochemical localization of nitric oxide neurons in the hypothalamus: association with gonadotropin-releasing hormone neurons and co-localization with N-methyl-D-aspartate receptors.

@article{Bhat1995HistochemicalLO,
  title={Histochemical localization of nitric oxide neurons in the hypothalamus: association with gonadotropin-releasing hormone neurons and co-localization with N-methyl-D-aspartate receptors.},
  author={Ganapathy K. Bhat and Virendra B. Mahesh and C A Lamar and Li Fang Ping and K Aguan and Darrell W Brann},
  journal={Neuroendocrinology},
  year={1995},
  volume={62 2},
  pages={187-97}
}
The neurotransmitter glutamate plays an important role in the control of gonadotropin-releasing hormone (GnRH) secretion. Recent evidence suggests that the novel transmitter nitric oxide may also play a role in controlling GnRH release and may be an important mediator of glutamate effects. To explore the role of nitric oxide in these events, the present study determined the distribution of the enzyme which catalyzes nitric oxide production, nitric oxide synthase (NOS) in the hypothalamus, its… CONTINUE READING

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