Histochemical identification of cortical areas in the auditory region of the human brain

  title={Histochemical identification of cortical areas in the auditory region of the human brain},
  author={Mark N. Wallace and Peter W. Johnston and Alan R. Palmer},
  journal={Experimental Brain Research},
Despite numerous studies stretching over the last 100 years there is still no general agreement on the number of auditory areas in the human cortex or even how to define them by histological methods. Full definition of these areas will require a combination of functional and histological methods but, by using six complementary histological methods, of which most have been used in the monkey, we provide a clearer description of these areas. The primary auditory area was located on the… 
Architectonic analysis of the auditory‐related areas of the superior temporal region in human brain
Architecture of auditory areas of the superior temporal region (STR) in the human was analyzed in Nissl‐stained material to see whether auditory cortex is organized according to principles that have
Anatomical organization of the auditory cortex.
  • T. Hackett
  • Biology
    Journal of the American Academy of Audiology
  • 2008
From these efforts, common features of structural and functional organization have begun to emerge from which a working model of human auditory cortex can be derived.
An anatomical and functional topography of human auditory cortical areas
A topography of areas is proposed that is consistent with old and recent anatomical post-mortem characterizations of the human auditory cortex and that may serve as a working model for neuroscience studies of auditory functions.
Patterns of calcium‐binding proteins support parallel and hierarchical organization of human auditory areas
Differences in intrinsic organization between auditory areas that are compatible with parallel and hierarchical processing of auditory information are suggested in analogy to non‐human primates.
Functional Topography of Auditory Areas Derived From the Combination of Electrophysiological Recordings and Cortical Electrical Stimulation
How the findings of this work help understanding the auditory semiology of certain epileptic seizures and, more generally, the neural substrate of hemispheric specialization for language are discussed are discussed.
Human Primary Auditory Cortex Follows the Shape of Heschl's Gyrus
Herschl's gyrus is significantly revised as a marker for human PAC and tonotopic maps may have shaped HG during human evolution, indicating the location of PAC across the range of common morphological variants of HG.
Heschl’s gyrus is more sensitive to tone level than non-primary auditory cortex


Human Primary Auditory Cortex: Cytoarchitectonic Subdivisions and Mapping into a Spatial Reference System
In future, the transfer of in vivo structural and functional data into the same spatial reference system will enable accurate comparisons of cytoarchitectonic maps of the primary auditory cortex with activation centers as established with functional imaging procedures.
Subdivisions of auditory cortex and ipsilateral cortical connections of the parabelt auditory cortex in macaque monkeys
Observations support the concept of dividing the auditory cortex into core, belt, and parabelt; provide evidence for including the rostral area in the core; suggest the existence of as many as seven or eight belt fields; provideevidence for at least two subdivisions of the parab belt; and identify regions of the temporal lobe involved in auditory processing.
Acetylcholinesterase staining in human auditory and language cortices: regional variation of structural features.
The pattern of AChE staining covaries with processing level in the hierarchy of auditory cortical regions, but does not vary between the functionally distinct right and left posterior regions.
Subdivisions of AuditoryCortex and Levels of Processing in Primates
The results indicate that auditory processing involves 15 or more cortical areas, each of which is interconnected with a number of other fields, especially adjoining fields of the same level.
Compartments within human primary auditory cortex: evidence from cytochrome oxidase and acetylcholinesterase staining
Comparison with tonotopic maps of human AI obtained by activation studies suggests that the cytochrome oxidase and acetylcholinesterase dark band is most likely parallel to isofrequency lines and may correspond to the representation of frequencies critical for speech comprehension.
Acetylcholinesterase‐rich neurons of the human cerebral cortex: Cytoarchitectonic and ontogenetic patterns of distribution
The existence of a specific laminar and cytoarchitectonic distribution suggests that the AChE‐rich enzymatic pattern of these neurons is selectively regulated.
Tonotopic organization of auditory cortical fields delineated by parvalbumin immunoreactivity in macaque monkeys
Neurons in the central core were sharply tuned and formed two complete tonotopic representations corresponding to the primary auditory area (AI) and the rostral (R) area, which were related to chemoarchitecture of the supratemporal plane, as delineated by immunoreactivity for parvalbumin.
Localization of the primary auditory area in man.
The localization of the primary auditory cortex in man was studied by direct recordings in 150 different sites in the superior transverse gyrus, especially in Heschl's gyrus and the planum temporale.
Auditory cortex on the human posterior superior temporal gyrus
Electrical stimulation of HG resulted in short‐latency EPs in an area that overlaps PLST, indicating that PLST receives a corticocortical input, either directly or indirectly, from HG.