Histochemical changes in the rabbit cornea and plasmin activity in the tear fluid during contact lens wear. Favourable influence of protease inhibitors (aprotinin, PC5, elastatinal)

@article{Cejkov1992HistochemicalCI,
  title={Histochemical changes in the rabbit cornea and plasmin activity in the tear fluid during contact lens wear. Favourable influence of protease inhibitors (aprotinin, PC5, elastatinal)},
  author={Jitka Cejkov{\'a} and Zdeněk Lojda and Jiř{\'i} Vac{\'i}k and George A. Digenis and S. Drop{\vc}ov{\'a}},
  journal={Histochemistry},
  year={1992},
  volume={97},
  pages={69-76}
}
Plasmin activity in the tear fluid of the rabbit eye was examined during the wearing of soft contact lenses (SCL) and compared with the occurrence of corneal disturbances assessed in cryostat sections. Plasmin activity was determined with a semiquantitative method using dry punches of filter paper previously soaked in 0.1 M Tris-HCl buffer solution containing mmol/l d-Val-Leu-Lys-FCA (trifluoromethylaminocoumarine), pH 7.2. Punches were applied to the corneal surface for 5 s (tear collection… CONTINUE READING