Histochemical and molecular overview of the thymus as site for T-cells development.

  title={Histochemical and molecular overview of the thymus as site for T-cells development.},
  author={Rita Rezzani and Francesca Bonomini and Luigi Fabrizio Rodella},
  journal={Progress in histochemistry and cytochemistry},
  volume={43 2},
The thymus represents the primary site for T cell lymphopoiesis, providing a coordinated set for critical factors to induce and support lineage commitment, differentiation and survival of thymus-seeding cells. One irrefutable fact is that the presence of non-lymphoid cells through the thymic parenchyma serves to provide coordinated migration and differentiation of T lymphocytes. Moreover, the link between foetal development and normal anatomy has been stressed in this review. Regarding thymic… CONTINUE READING

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