Histochemical and immunohistochemical evidence of tumor heterogeneity in colorectal cancer.


INTRODUCTION Intratumoral heterogeneity implies the existence of differences between tumor cells, which can best be shown by histochemical and immunohistochemical techniques. The histological study is a mandatory step in any research aimed at characterizing tumor heterogeneity. Immunohistochemistry (IHC) also plays an important role in the differentiation… (More)

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