Histochemical and X-ray microanalytical localization of aluminum in amyotrophic lateral sclerosis and parkinsonism-dementia of Guam

@article{Piccardo1988HistochemicalAX,
  title={Histochemical and X-ray microanalytical localization of aluminum in amyotrophic lateral sclerosis and parkinsonism-dementia of Guam},
  author={Pedro Piccardo and Richard Yanagihara and Ralph M. Garruto and Clarence J. Gibbs and D. Carleton Gajdusek},
  journal={Acta Neuropathologica},
  year={1988},
  volume={77},
  pages={1-4}
}
Histochemical staining for aluminum, using Solochrome azurine or Morin, provided a rapid, simple and reliable means of identifying areas and structures of the brain of interest for closer scrutiny by X-ray microanalysis in patients with amyotrophic lateral sclerosis and parkinsonism-dementia of Guam. Neuronal perikarya, dendritic processes, and the walls of some cerebral vessels were aluminum positive by Solochrome azurine staining. In some cases, the deposition of aluminum was rather diffuse… CONTINUE READING
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