Histiocytosis and a leukaemoid response. A case report.

  title={Histiocytosis and a leukaemoid response. A case report.},
  author={Matthew Richard Leibowitz and Israel S. Freiman and Lorna G. Macdougall and Robb Jacobson and Kristian Stevens},
  journal={South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde},
  volume={53 11},
A patient with all the clinical signs of Letterer-Siwe disease is reported. The patient was unusual in that he had a severe leukaemoid reaction. To our knowledge, only 2 similar patients with reticulo-endotheliosis, histiocytic skin infiltration and leukaemoid reaction have been reported. It is possible that the disorder may represent a variant of the histiocytic proliferative disorders, characterized by both histiocytic and myeloid hyperplasia, and is thus similar to myelomonocytic leukaemia… CONTINUE READING

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